Test tube rack of analyzer pipeline, shift detection method and device using the same

ABSTRACT

A test tube rack of an analyzer pipeline includes multiple test tube holders for holding test tubes. The test tube rack of an analyzer pipeline comprises a light blocker configured at a side wall of the test tube rack and across multiple test tube holders. A second feature area is on the light blocker between two adjacent test tube holders, a first feature area is between two adjacent second feature areas and a step gap with a predetermined depth is between the first feature area and a second feature area.

TECHNICAL FIELD

The present disclosure relates to a test tube rack of an analyzerpipeline, especially relating to an analyzer pipeline system, a testtube rack thereof, a shift detection method and a device using the same.

BACKGROUND

On a pipeline of a blood cell analyzer, a test tube rack carrying testtubes (with blood samples) is transported from a loading platform to adetecting area of the blood cell analyzer by a transporting belt along atrack. The test tube rack is shifted one step each time so that eachtest tube carried on the test tube rack is passed through a test tubedetector and a sample needle one by one to let the analyzer detect thereference code of the test tube and conduct sample collections. Thedistance of one shift step is defined as the width of one test tubeunit. For certain reasons, such as lost steps of a stepper motor, thetest tube rack may shift to a wrong position (the test tube fails tomove to a predetermined position), which would cause wrong referencecodes to be detected by the test tube detector and wrong samples to besampled by the sample needle, so as to make test results fail to matchthe right sample provider (patient). Obviously, such mis-operationswould cause many risks in clinical settings.

To avoid the mentioned clinical risks, an operation for testing whetherthe test tube rack is shifted to the right position in the pipelineshould be conducted. A warning is raised when the test tube rack isshifted to the wrong position. In the conventional method, bydistinguishing the differences of reflected signals from differentareas, an optical detector is used to detect a feature area on the backside of the test tube rack to implement the above position detection.

Referring to FIG. 1, a middle portion between two test tube holders ofthe back side of test tube rack 101 is processed to form a groove with a6 mm depth. The test tube rack 101 is formed as a through hole with arectangular shape front to back at the location of the test tube holderof the test tube rack 101. A narrower edge 103 is defined between agroove 104 and a rectangular hole 105. The optical detector aims thecenter of the groove 104 by adjusting positions. The test tube rack 101is shifted a width of the test tube holder one time then the opticaldetector is directed to aim at the next groove from the currently aimedgroove. In this process, the optical detector detects five featureareas; they are a first groove, a first edge, a test tube, a second edgeand a second groove respectively (the test tube is detected since it islocated at the rectangular hole of the rack). Because the distancebetween the groove or the test tube and the optical detector is far, thereflected light from the groove or the test tube to the optical coupleris weak. The reflected light from the edge to the sensor is strong sincethe distance between the edge and the optical coupler is close.Therefore, the feature of the reflected signal shown in the shiftingprocess would be presented as low-high-low-high-low.

In general, an absolute value determination method is applied in theabove signal detection. In the absolute value determination method, athreshold voltage is marked between a groove signal and an edge signalat first, and each voltage signal generated in the sifting process ofthe test tube rack is used to compare with the threshold voltage. If twovoltage signals with an impulse higher than the threshold voltage aredetected, it means two edges of the rack have passed through. In otherwords, the above result proves the rack has shifted to the rightposition. However, since the detection areas of the sensor include thetest tube, the reflected signals reflected in certain angles from aglass test tube with a sample inside could be over the threshold valueto generate a false impulse if a tag is not pasted on the test tube.Even when a tag is pasted on the test tube, the surface of some specifictag types may be too bright and cause the reflected signals from the tagthat are still too strong to generate a false impulse. Therefore,multiple impulses higher than the threshold voltage may be detectedbetween two grooves so as to cause a false negative determination evenwhen the test tube rack is shifted to the wrong position. Under theabove, conventional skills for detecting the shift state of the testtube rack are not reliable; it still contains chances for wrong ormissing detections, so the clinical risk still exists.

In addition, for figuring out clinical issues, such as temperaturevariances, sensor aging, and errors of the track (the track has acertain width; a 1 mm tolerance should be defined under the above width)causing the value of reflected signals floating over the thresholdvoltage to affect the viability of the detecting result, ahigh-performance sensor/optical detector is the only choice to implementthe above conventional solution since only the optical detector hasenough sensitivity to satisfy the high demand of the above solution. Thepurpose for applying the optical detector is to enlarge the differencesbetween the groove signal and the edge signal as much as possible.However, the optical detector is so expensive that it causes the cost ofthe blood cell analyzer to be significantly high, which restricts theimplementation of the detection technology for detecting displacementissues of the test tube rack.

SUMMARY

Therefore, a test tube rack of an analyzer pipeline, a shift detectionmethod and a device using the same are provided.

A test tube rack of an analyzer pipeline that includes multiple testtube holders for containing test tubes is provided. The test tube rackof an analyzer pipeline includes a light blocker configured at a sidewall of the test tube rack and across multiple test tube holders. Asecond feature area is on the light blocker between two adjacent testtube holders, a first feature area is between two adjacent secondfeature areas and a step gap with a predetermined depth is between thefirst feature area and a second feature area.

In one embodiment of the method for fusing at least one ultrasound imageand a pre-acquired modality image of the present invention, multipleframes of ultrasound images are selected in the selecting step. Themethod further includes a breath model built step and abreath-correcting step. The breath model built step is for building abreath model according to the ultrasound video data. Thebreath-correcting step is conducted before the registering step orduring the fusion step for implementing the breath model to correct themultiple frames of ultrasound images into the same breath depth level.

A shift detection method implemented by using the test tube rackincludes acquiring a detection signal outputted from a sensor in asingle shifting process of the test tube rack, a stop voltage from thedetection signal when the single shifting process ends and a limitvoltage from the detection signal during the single shifting processfrom the detection signal. Determining whether a ratio of the limitvoltage and the stop voltage satisfies a first condition. If the firstcondition is satisfied, the single shifting process of the test tuberack is determined as correct; otherwise, the single shifting process ofthe test tube rack is determined to be false.

A detecting device using the test tube rack of the analyzer pipelineincludes a voltage acquisition module and a shift determination module.The voltage acquisition module acquires a detection signal outputtedfrom a sensor in a single shifting process of the test tube rack, a stopvoltage from the detection signal at the end of the single shiftingprocess and a limit voltage from the detection signal during the singleshifting process. The shift determination module determines whether aratio of the limit voltage and the stop voltage satisfies a firstcondition. If the first condition is satisfied, the single shiftingprocess of the test tube rack is determined as correct; otherwise, thesingle shifting process of the test tube rack is determined as false.

An analyzer pipeline system includes: an analyzer; a test tube rack; adriving apparatus for driving the test tube rack; a sensor for detectinga first feature area and a second feature area in a shifting process ofthe test tube rack and outputting a detection signal correspondingly;and a processor including a detecting device for detecting the shift ofthe test tube rack. The detecting device, coupled to an output of thesensor, receives the detection signal outputted from the sensor todetermine whether the shifting process of the test tube rack is correct.

The test tube rack only includes the first feature areas and the secondfeature areas for shift detection; the detecting area for the sensoravoids detecting the area of the test tubes so that the detectionsignals are not influenced by the reflected signals generated from thetest tubes and tags. Therefore, no test tube would be lost for detectionwhen the shifting process of the test tube is false so as to keep thereliability of the pipeline system.

The shift detection method disclosed in the present embodiment is arelative value signal detecting algorithm in a feature area. Under thisalgorithm, the sensitivity requirement for the implemented reflectiveoptical sensor could be significant reduced. Basically, it could besatisfied by a general type reflective optical sensor so as to reducethe cost of reflective optical sensors.

BRIEF DESCRIPTION OF THE DRAWINGS

For explaining the embodiments of the present application orconventional technology more clearly, the figures used for explainingthe embodiments or conventional background are introduced below.Obviously, in the drawings, similar drawings contain similar symbols forthe same device or part, or for a part which has an analogous functionand/or analogous structure. It should be understood that these drawingsdescribe different kinds of embodiments, but are not to be considered aslimitations of their scope.

FIG. 1 is a structure schematic of a conventional test tube rack of ananalyzer pipeline.

FIG. 2 is a working schematic of an analyzer pipeline with a test tuberack and shift detection device thereof for one embodiment of thepresent application.

FIG. 3 is a structure schematic of a test tube rack for one embodimentof the present application.

FIG. 4 is a diagram of a general type reflective sensor shown with acharacteristic curve relating to its reflecting signal/distancerelationship (distance sensitivity curve).

FIG. 5 is a process schematic of a shift detection method for a testtube rack applied in an analyzer pipeline of one embodiment of thepresent invention.

FIG. 6 is a schematic of a detection signal recording all changes in onesingle shifting process for a test tube rack.

FIG. 7 is a schematic of a detection signal recording all changes in onesingle re-shifting process for a test tube rack.

FIG. 8 is a module schematic of a shift detection device of the testtube rack for one embodiment of the present application.

FIG. 9 is a partial detail circuit diagram of a shift detection deviceof the test tube rack for one embodiment of the present application.

DETAILED DESCRIPTION

Specific details for fully understanding each of embodiments andimplemented by those skilled in the art are provided in the belowdescription. However, it should be understood for those skilled in theart that the present invention is able to be implemented without thespecific details as well. In some embodiments, conventional structuresand functions are omitted to avoid confusion in the descriptions of theembodiments.

Unless it is acquired clearly under context of the descriptions, theterms “comprise” and “include” should be defined as an openingdefinition but not as a limited or an exhaustive definition.

FIG. 2 is a working schematic of an analyzer pipeline with a test tuberack and shift detection device thereof for one embodiment of thepresent application. The analyzer pipeline is able to include one ormultiple analyzers, but only one analyzer is shown in FIG. 2. Thepresent embodiment is also described under one analyzer structure. Theabove analyzer could be selected from a blood cell analyzer, abiochemistry analyzer or a smear machine. In the pipeline, a test tuberack 201 is transported to a detection area of an analyzer 202. A testtube 203 is shifted one test tube holder at a time to pass through afirst sensor 205 located on a test tube detecting position 204 andthrough a second sensor 207 located on a sample collecting position 206in sequence. Because a block apparatus 208 is implemented to block thetest tube rack at a target position for each shifting step of thepipeline, the test tube rack cannot be shifted ahead but can only beleft behind because of the lost steps of a motor, slip of a shiftingbelt or delay for pasting a tag. Therefore, the shift detection for thetest tube rack needs to detect only whether the test tube rack is leftbehind in its predefined location, whether the backward distance isunder allowable ranges and whether the test tube rack is shifted on thepredefined location precisely. An arrow symbol 209 shown in FIG. 2defines the shifting direction of the test tube rack.

Referring to FIG. 3, a plurality of test tube holders, which are able tocarry a test tube 301, are configured at a test tube rack of a pipeline.A light blocker 300, which spans multiple test tube holders, is formedon one side of the test tube rack (such as the side of the rack facingthe light sensor). A second feature area 303 is configured on the lightblocker 300 between two adjacent test tube holders. A first feature area302 is configured between two adjacent second feature areas 303. A stepgap with a predetermined depth is formed between the first feature area302 and the second feature area 303. The first feature area 302 and thesecond feature area 303 are configured on the light blocker 300alternately and consistently.

In one embodiment, the second feature area 303 is a groove with apredetermined depth lower than the first feature area 302, or the secondfeature area 303 is a protrusion with a predetermined height higher thanthe first feature area 302. In the embodiment of the presentapplication, for explaining but not restricting, the second feature area303 is defined as a groove with a predetermined depth lower than thefirst feature area 302.

It should be noted that the first feature area 302 could be an areawithout any machining work. Actually, it could be the original side wallof the test tube rack. The step gap between the first feature area 302and the second feature area 303 could be formed by machining the secondfeature area 303. For example, the second feature area 303 could bemachined as a groove with a predetermined depth lower than the firstfeature area 302 or a protrusion with a predetermined height higher thanthe first feature area 302. Obviously, in another embodiment, it is alsoworkable by machining the first feature area 302 to realize the step gapbetween the first feature area 302 and the second feature area 303.Alternatively, in some other embodiment, the first feature area 302 andthe second feature area 303 could be machined as a groove and aprotrusion individually, or instead, as a protrusion and a groove on thecontrary.

In the embodiment, the second feature area 303 is selected as a groovewith a predetermined depth lower than the first feature area 302. Thepredetermined depth of the groove is between 5 and 7 mm; moreparticularly, 6 mm could be selected. Under the above, the first featurearea 302 is shaped as a protrusion correspondingly. It should be notedthat the detection signal from the sensor should be a light beam whenthe sensor is implemented as a reflective optical sensor; a light beamhas a cross-section which is defined as a facula (light spot). Ingeneral, the width of the first feature area 302 and the second featurearea 303 should both be larger or at least equal to the facula of thelight beam. However, in some other embodiments, the width of the firstfeature area 302 and the second feature area 303 could also be a littlebit smaller than the facula of the light beam, but only under thecondition that the reflected light from the first feature area 302 andthe second feature area 303 still has distinguishable differences ofstrength. In the present embodiment, the width of the second featurearea 303 is configured as 6 mm and the width of the first feature area302 is referred to as the width of the test tube holder. In anotherembodiment, a sound sensor, such as an ultrasound sensor, could beimplemented to detect the first feature area 302 and the second featurearea 303 according to the strength of reflecting ultrasound waves.

The light blocker 300 could be selectively configured at the upperportion or the down portion of the side wall of the test tube. In thepresent invention, the light blocker 300 is configured at the upperportion of the side wall of the test tube to strengthen the stability ofthe test tube rack. Since many other parameters are needed to bedetected by the analyzer in the analyzing process, a third feature area304 is configured at a portion of the side wall which is not defined asthe light blocker 300. The third feature area 304 is configured at twosides of the test tube holder, and is defined as a groove with apredetermined depth lower than the side wall of the test tube rack or aprotrusion higher than the side wall of the test tube rack. The sidewall of the test tube rack is the side of the rack pasted with the lightblocker 300, shown as 305 in FIG. 3. On the other hand, the test tubeholder is still maintained as a through hole with a rectangular shapefront to back for implementing the detection of other parameters, suchas scanning a tag on a test tube.

When the test tube rack of the present application is conducting a shiftdetection, the distance between the optical coupler and the firstfeature area 302 is approximately at the peak point of the reflectingsignal strength by adjusting the position of the test tube rack to aimthe focal point on the center of the groove (the second feature area303). Every time the test tube rack is shifted, the sensor scans andaims on the center of the next groove after aiming on the center of theprevious groove. Under the above, the distance between the reflectingsurface of the reflected light and the sensor is recorded for containinga far-close-far change in the shifting process. Synchronously, thestrength of the reflecting signal containing a high-low-high change isalso recorded in the shifting process. In the present application, thedepth of the test tube rack groove is 6 mm. For a general typereflective optical sensor, a 6 mm step gap would cause a not less than50% change of signal strength for the reflected signal generated by thegeneral type reflective optical sensor so as to ensure the accuracy ofabove sifting detection.

FIG. 4 is a diagram of a general type reflective optical sensor showinga characteristic curve relating to its reflecting signal/distancerelationship (distance sensitivity curve). It is shown that when thedistance between the reflecting surface and the sensor increases from0.2 inch to 0.42 inch, the detected reflecting signal decays to 50% (1inch equals). It is enough to provide an appropriate sensitivity forsensing reflected light under the above; therefore, different fromconventional implementations, the requirements of the shift detection ofthe test tube rack are satisfied only by implementing a general typereflective optical sensor in the present application.

A 6 mm wide by 6 mm deep strip-shaped groove is configured between twoadjacent test tube holders at the upper portion of the side wall of thetest tube rack in the present application. A test tube holder 20 mm wideis configured between two adjacent grooves, and the upper portion of thetest tube holder between two adjacent grooves 320 is the complete firstfeature area 302 (plate) but not a passing-through structure like theconventional one. Therefore, the whole structure of the upper side wallof the test tube rack in sequence is a continuous combination comprisinga “the groove 303-the plate 302-the groove 303-the plate 302-the groove303 . . . ” structure. On the other hand, if the second feature area 303is configured as a protrusion, the whole structure of the upper sidewall of the test tube rack in sequence is a another continuouscombination comprising a “the protrusion 303-the plate 302-theprotrusion 303-the plate 302-the protrusion 303 . . . ” structure. Sincethe test tube holder (the first feature area 302) is not apassing-through structure, the test tube 301 would not be detected bythe sensor so that the reflecting signal would not be influenced byreflected light from the test tube 301 or the code tag pasted on it.Under the above implementation, the sensor could avoid a wrongdetermination for the shifting state of the test tube rack caused byfalse high-reflective signals.

FIG. 5 discloses a process schematic of a shift detection method for atest tube rack applied in an analyzer pipeline of one embodiment of thepresent invention, which comprises:

STEP 501: acquiring a detection signal inputted from a sensor from asingle step shifting process of a test tube rack. The single stepshifting is defined as the step from when the test rack tube starts itsshift to when the shift is stopped.

STEP 502: amplifying and digital filtering the detection signal toremove error influences caused from noises or an uneven surface of thetest tube rack. In the present embodiment, a middle value filteringalgorithm is selected to implement the above process.

STEP 503: an initial voltage V_ORI, defined as the voltage valuedetected when the test tube rack starts to shift; a stop voltage V_END,defined as the voltage value detected when the test tube rack ends itsshift; and a limit voltage V_EXT, defined as the maximum absolute valueof voltage from the beginning to the end of the shift of the rack, areacquired from the detection signal after the digital filtering processin STEP 502.

It should be noted that when the second feature area is configured as agroove, the value of the detection signal should correspondingly become“ . . . low-high-low-high-low . . . ” and the limit voltage V_EXT shouldbe detected as a maximum voltage V_MAX. On the contrary, when the secondfeature area is configured as a protrusion, the value of the detectionsignal should correspondingly become “ . . . high-low-high-low-high . .. ” and the limit voltage V_EXT should be detected as a minimum voltageV_MIN. In the present embodiment, for explaining but not restricting,the limit voltage V_EXT is selected as the maximum voltage V_MAX byconfiguring the second feature area as a groove.

FIG. 6 shows a schematic of a detection signal recording all changes inone single shifting process for a test tube rack. Firstly, the initialvoltage V_ORI is detected when the test tube rack starts to shift anddefines the position of V_ORI as a starting point; after that, the stopvoltage V_END is detected when the test tube rack ends its shift anddefines the position of V_END as an ending point. Since thegroove-plate-groove structure of the test tube rack is shifted throughthe sensor in sequence, the detection signal from the sensor wouldcorrespondingly represent as a bell-shaped curve; the maximum voltageV_MAX is acquired between the starting point and the ending point. Whenthe second feature area of the test tube rack is configured as aprotrusion, the detection signal from the sensor would correspondinglyrepresent as an upside-down bell-shaped curve; the minimum voltage V_MINis acquired between the starting point and the ending point.

STEP 504: determining whether the ratio of V_MAX and V_ORI satisfies asecond determining condition and whether the ratio of V_MAX and V_ENDsatisfies a first determining condition. If the first determiningcondition and the second determining condition are both satisfied, theshifting state of the test tube rack is determined as correct.Otherwise, the shifting state of the test tube rack is determined asfalse. It should be understood that, in other applications, by merelydetermining whether the ratio of V_MAX and V_END satisfies the firstdetermining condition, the shifting state of the test tube rack couldalso be determined. When the ratio of V_MAX and V_END satisfies thefirst determining condition, it is determined that the shifting state ofthe test tube rack is correct. If the first determining condition is notsatisfied, the shifting state of the test tube rack is determined asfalse. In the present embodiment, for making sure the accuracy of theshifting state determination, the judgment of the ratio of V_MAX andV_ORI is further implemented.

In the present embodiment, the first determining condition is defined asthe ratio of V_MAX and V_END is larger than a first factor k1, and thesecond determining condition is defined as the ratio of V_MAX and V_ORIis larger than a second factor k2, which are shown as the belowfunctions:

V_MAX/V_END>k1  function (1)

V_MAX/V_ORI>k2  function (2)

In the present embodiment, k1 and k2 are both a constant number largerthan 1. Decisions about how to get a suitable value for k1 and k2 relateto the relative difference between the detection signal of the plate ofthe test tube rack and the detection signal of the groove of the testtube rack. When the relative difference is larger, k1 and k2 areincreased correspondingly. The relative difference, under the abovedisclosures, relates to characteristic factors such as the reflectingsignal —distance feature or the depth of the groove. In one embodiment,for general type reflective optical sensors, k1 and k2 are defined as avalue 1.5-2.0 under the condition that the depth of the test tube rackgroove is defined as 6 mm. Usually, k1 and k2 could be selected as thesame value.

In another embodiment, when the second feature area is defined as aprotrusion, the first determining condition is defined as the ratio ofV_MIN and V_END is smaller than a third factor k3, and the seconddetermining condition is defined as the ratio of V_MIN and V_ORI issmaller than a fourth factor k4, which are shown as the below functions:

V_MIN/V_END<k3  function (3)

V_MIN/V_ORI<k4  function (4)

Wherein k3 and k4 are constants whose values are both between 0 and 1,decisions about how to get a suitable value for k3 and k4 are similar tothose of k1 and k2, so those factors are omitted for clarity of thedescriptions thereof.

In a single shifting process, when function (1) and function (2) areboth found, it means that V_ORI is corresponding to a groove area of thetest tube rack, V_END is corresponding to the next groove area of thetest tube rack and V_MAX is corresponding to the plate area of the testtube rack. The above changes prove the shifting process of the test tuberack is passed through a groove-plate-groove process and the test tuberack is definitely shifted to a right locating position. In the otherwords, the shifting state of the test tube rack is defined as correctunder the above. If the function V_MAX/V_END>k1 is not found, it meansthe previous groove of the rack has left the sensing area of the sensorbut the next groove of the rack is not shifted to the same sensing areain sequence, which explains why the present plate area of the rackstayed at the sensing area of the sensor. In other words, the shiftingstate of the test tube rack is defined as false under the above. If thefunction V_MAX/V_ORI>k2 is not found, it means the test tube rack wasstuck at the pipeline and the previous plate area of the rack stayed atthe sensing area of the sensor. Usually, when a false state of theshifting process happens, a correction step would be conducted beforerestarting the next shifting process. Therefore, function (2) isbasically sustained under normal situations.

STEP 505: controlling the test tube rack for conducting a re-shiftprocess, and acquiring the detection signal outputted from the sensor inthe re-shift process. The re-shift process is defined as an additionalshifting process which controls the test tube rack to be shifted againto relocate the test tube rack at the right locating position when theshifting process of the test tube rack is determined as false atpresent. It should be noted that the driving mechanism controlling theshifting process of the test tube rack is normally implemented by astepper motor. A stepper motor is capable of moving at a specific steplength which equals the distance of a single shift of the test tuberack. In the re-shift process, the shifting distance is obviouslysmaller than the step length of the stepper motor. It means the steppermotor can drive the test tube rack to shift only its original steplength. However, since a blocker mechanism is implemented just at theright locating position, the blocker would block the test tube rack tostay at the right locating position so that the over-shifting situationof the test tube rack has no chance to happen under the aboveimplementation.

STEP 506: considering the detection signal of the previous shiftingprocess with the detection signal of the re-shift process to re-acquirethe initial voltage, the stop voltage and the maximum voltage, andre-conducting STEP 504 again. In another embodiment, if only V_ENDvoltage is acquired for determining whether the shifting process of thetest tube rack is false in STEP 503, correspondingly, an implementationin which only V_END voltage is re-acquired after the re-shift process isconducted is also workable.

In one embodiment, details for implemented STEP 505 and STEP 506 aredisclosed as below: Buffering the two feature signals V_ORI voltage andV_MAX voltage and re-shifting the test tube rack to acquire threefeature signals during the re-shifting process, which are V_ORI, V_MAXand V_END. After the above, comparing the V_ORI voltage buffered in thepipeline system with the V_ORI voltage acquired during the re-shiftingprocess to choose the one with lower voltage then renew V_ORI as thelower value. After that, comparing the V_MAX voltage buffered in thepipeline system with the V_MAX voltage acquired during the re-shiftingprocess to choose the one with higher voltage then renew V_MAX as thehigher value. After that, implementing the renewing V_ORI, renewingV_MAX and V_END acquired during the re-shifting process to conduct thedetermination of function (1) and function (2). If the determination offunction (1) and function (2) is satisfied, it proves the test tube rackreaches the right locating position at the end. If the determination offunction (1) and function (2) is not satisfied, it means the re-shiftingprocess is false and the test tube rack does not reach the rightlocating position still. Another implementation for acquiring therenewing V_ORI, renewing V_MAX and V_END acquired during the re-shiftingprocess is disclosed below: saving the whole detection signal (the wavecurve) from the beginning point to the ending point, and mapping all thecurve of above with the detection signal (the wave curve) acquiredduring the re-shifting process to find the three feature points V_ORI,V_MAX and V_EDN.

Normally, the step of buffering data does not exist in the disclosedshift detection method of the test tube rack. Acquired data in theprevious step would be replaced by the new data acquired at the nextprocess. However, in the present application, the buffering step isimplemented in the shift detection method of the test tube rack.Therefore, the feature voltages or the whole detection signal acquiredin the shifting process could be saved respectively to conduct there-shifting process.

It should be noted that the re-shifting can be conducted for only onetime or for multiple times until the renewing V_ORI, V_MAX and V_ENDsatisfy with the determination condition since that shows the test tuberack has shifted to the right locating position.

FIG. 7 shows a schematic of a detection signal recording all changes inone single re-shift process for a test tube rack in a detailedembodiment. The test tube rack is stuck at some specific positioncorresponding to a signal rising edge and the corresponding V_MAX equalsthe V_END under the above situation, which is not satisfied with thefunction of V_MAX/V_END>k1, so that a re-shifting process is initiatedautomatically. The peak point of the detection signal is detected at thefirst re-shifting process, which means the plate area of the rackreaches the right locating position, but the V_END is still too high,which means the test tube rack is still stuck at some specific positioncorresponding to some signal falling edge, to fail the determiningcondition. Therefore, a second re-shifting process is conductedaccordingly. In the second re-shifting process, the V_END valuecorresponding to the groove area of the test tube rack is detected,which means the test tube rack is shifted to the right locatingposition, and V_MAX is still holding on the peak value acquired at thefirst re-shifting process so that the determining condition issatisfied. It is understood, by comparing FIG. 6 with FIG. 7, thatalthough multiple re-shifting processes are conducted, the detectedmaximum voltage, the beginning voltage and the ending voltage arerespectively the same as the corresponding values detected when thedetermining condition is satisfied at a single shifting process. Itmeans, for the implementation disclosed in the present application, keyfeatures of the detection signal would not be lost, and key features ofdetected signals acquired at the re-shifting process are the same asdetected signals acquired when the determining condition is satisfied ata single shifting process. Therefore, the whole shifting processdisclosed in the present embodiments supports high reliability and theissue of false negative detection is avoidable accordingly.

The shift detection method disclosed in the present embodiment is arelative value signal detecting algorithm in a feature area. Under thisalgorithm, the sensitivity requirement for the implemented reflectiveoptical sensor could be significantly reduced. Basically, it could besatisfied by a general type reflective optical sensor so as to reducethe cost of reflective optical sensors.

In a conventional shift detection method of the test tube rack, it canonly stop the pipeline and raise a warning when the test tube rack isnot shifted to the right locating position at the first time in theshifting process. The pipeline system does not automatically re-conductone or multiple re-shifting processes to exclude faults, which is notintelligent and could cause inconvenience for the user. A re-shiftingprocess is embodied in the present embodiment, which means a recoveringdetection algorithm for a breakdown point of the pipeline system isimplemented. When the test tube rack is not shifted to the rightlocating position at the first time shifting process, it is possible toautomatically re-shift the test tube rack through the above breakdownpoint recovering algorithm until the test tube rack is shifted to theright locating position. The above embodiment is significantly moreintelligent, so the user experience is accordingly better. Those skilledin the art will understand that, excepting the technical solutionsdisclosed in the present embodiment, other detection solutions could beimplemented alternatively, such as the conventional absolute valuedetection solution.

FIG. 8 shows a module schematic of a shift detection device of the testtube rack for one embodiment of the present application. In the presentembodiment, the detection device for shift detection of the test tuberack comprises a feature voltage acquisition module 601 and a shiftingdetermination module 602.

The feature voltage acquisition module 601 is implemented for acquiringthe detection signal outputted from the sensor in the single timeshifting process of the test tube rack. The feature voltage acquisitionmodule 601 acquires the initial voltage when the test tube rack startsto be shifted, the stop voltage when the test tube rack ends its shiftand the limit voltage among the shifting process of the test tube rack.

The shifting determination module 602 is implemented to determinewhether the first determining condition is satisfied by the ratiobetween the limit voltage and the end voltage. If it is satisfied, thetest tube rack is shifted to the proper locating position. If it is notsatisfied, the test tube rack has failed to shift to the correctlocation, or right locating position.

In the present embodiment, the feature voltage acquisition module 601further acquires the initial voltage when the test tube rack starts tobe shifted in the single shifting process of the test tube rack afterthe detection signal outputted from the sensor in the single timeshifting process is acquired. The shifting determination module 602determines whether the second determining condition is satisfied by theratio between the limit voltage and the initial voltage for the firstdetermining condition to be determined. If both the first determiningcondition and the second determining condition are satisfied, the testtube rack is shifted to the right locating position. Otherwise, thedetermination of the shifting process of the test tube rack is false.

In the present embodiment, the first determination condition is definedas whether the ratio between the limit voltage and the stop or endvoltage is larger than the first factor, and the second determinationcondition is defined as whether the ratio between the limit voltage andthe initial voltage is larger than the second factor. In anotherembodiment, the first determination condition is defined as whether theratio between the limit voltage and the stop voltage is smaller than thefirst factor, and the second determination condition is defined aswhether the ratio between the limit voltage and the initial voltage issmaller than the second factor.

In one embodiment, the shifting determination module 602 is able tocontrol the warning device to initiate a warning when the shiftingdetermination module 602 detects the shifting process of the test tuberack has failed.

In the present embodiment, the detection device for shift detection ofthe test tube rack comprises a re-shifting module 603. The re-shiftingmodule 603 is implemented to control the re-shifting process of the testtube rack after the shifting determination module 602 detects theshifting process of the test tube rack has failed and to acquire thedetection signals outputted from the sensor during the re-shiftingprocess to renew the limit voltage, the stop voltage and the initialvoltage by comparing the detection signal acquired at the previousshifting process. After the above, the shifting determination module 602determines whether the ratio between the renewing limit voltage and therenewing stop voltage satisfies the first determining condition, andwhether the ratio between the renewing limit voltage and the renewinginitial voltage satisfies the second determining condition. If both thefirst determining condition and the second determining condition aresatisfied, it is determined that the shifting of the test tube rack iscorrect. Otherwise, the re-shifting module 603 is controlled to conductthe re-shifting process until the shifting of the test tube rack iscorrect. It should be noted that, if the determination of whether theratio between the limit voltage and the stop voltage satisfies the firstdetermining condition conducted in the previous shifting process, onlythe limit voltage and the stop voltage should be renewed during there-shifting process of the test tube rack.

In the present application, details about how the re-shifting module 603re-shifts the test tube rack and re-acquires the initial voltage, thestop voltage and the limit voltage are described as below:

During the re-shifting process, the initial voltage, the stop voltageand the limit voltage are acquired from the detection signal outputtedfrom the sensor. The above voltages are compared with the initialvoltage, the stop voltage and the limit voltage from the detectionsignal outputted from the sensor buffered in the previous shiftingprocess. The smaller of the above two initial voltages is selected as apresent initial voltage. The larger of the above two limit voltages isselected as a present limit voltage when one of above two limit voltagesis at its peak value. Alternatively, the smaller one of above two limitvoltages is selected as a present minimum value voltage when one ofabove two limit voltages is at its minimum value. The stop voltageacquired at the re-shifting process is selected as a present endvoltage. In another embodiment, the re-shifting model 603 integratesdetection signals outputted from the sensor in multiple re-shiftingprocesses as a complete detection signal, and the present initialvoltage, the limit voltage and the present stop voltage are selectedfrom the complete detection signal.

The shift detection method disclosed in the present embodiment is arelative value signal detecting algorithm in a feature area. Under thisalgorithm, the sensitivity requirement for the implemented reflectiveoptical sensor could be significantly reduced. Basically, it could besatisfied by a general type reflective optical sensor so as to reducethe cost of reflective optical sensors.

The analyzer pipeline system in one embodiment includes one or multipleanalyzers, the test tube rack provided in the above embodiment, adriving mechanism for driving the shift of the test tube rack, a sensorfor detecting the first feature area and the second feature area in theshifting process of the test tube rack and outputting the correspondingdetection signals, and a processor, the processor including a detectingdevice for detecting the shift of the test tube rack, the detectingdevice, coupled to the output terminal of the sensor, receiving thedetection signals outputted from the sensor to determine whether thetest tube rack is shifted to the right locating position.

In one embodiment, the detecting device acquires the initial voltage atthe beginning of a single shift process of the test tube rack accordingto the detection signals outputted in accordance with the first featurearea and the second feature area. The detecting device further acquiresthe stop voltage at the end of the shifting process and the limitvoltage between the beginning and the end of the shifting process. Afterthat, the detecting device determines whether the ratio of the limitvoltage and the stop voltage satisfies the first determining conditionand whether the ratio of the limit voltage and the initial voltagesatisfies the second determining condition. If both conditions aresatisfied, the shifting process of the test tube rack is determined ascorrect; otherwise, it is determined as false.

The detecting device is also implemented for controlling the re-shiftingprocess of the test tube rack if the shifting process of the test tuberack is determined as false. The detecting device further acquires thedetection signals outputted from the sensor during the re-shiftingprocess to combine the above with the detection signals acquired in theprevious shifting process to regain the initial voltage, the stopvoltage and the limit voltage. If the ratio of the limit voltage and thestop voltage satisfies the first determining condition and the ratio ofthe limit voltage and the initial voltage satisfies the seconddetermining condition, the test tube rack is determined as shifting tothe right locating position. Otherwise, the re-shifting process of thetest tube rack is conducted again until the test tube rack is shifted tothe right locating position.

Referring to FIG. 2, in the present embodiment, the sensor includes thefirst sensor 205 and the second sensor 207 and the first sensor 205 isconfigured at the test tube detecting position 204 and the second sensor207 is configured at the sample collecting position 206. In the presentembodiment, the first sensor 205 and the second sensor 207 areimplemented by two identical reflective optical sensors. The firstsensor 205 is used to confirm whether the test tube rack is shifted tothe test tube detecting position 204 since a wrong shift of the testtube 203 could cause wrong tag-numbering of the test tube 203 (sample).The second detector 207 is configured at the sample collecting position206. A wrong shift at the sample collecting position 206 could causemis-collection of samples. In general, the test tube rack has 10 testtube holders. There are six intervals of test tube holders between thefirst sensor 205 and the second sensor 207. In some other embodiments,interval numbers between the first sensor 205 and the second sensor 207could be configured under detailed requirements. Since six intervals areconfigured between the first sensor 205 and the second sensor 207 andthere are 10 test tube holders for a test tube rack, the test tube rackcould be detected by the above two detectors at the same time when thetest tube rack is shifted to certain positions. In the above situation,the pipeline system is workable to take detection results only from afixing detector selected from the above two. The reason to configure twodetectors in some embodiments is to make sure that the shift detectioncan be conducted for all the test tubes at any time when test tubedetection and sample collection are conducted on all the test tubes.

Of course, in some embodiments, one detector could be implemented forshift detection, but for making sure that shift detection can beconducted for all the test tubes at any time when test tube detectionand sample collection are conducted on all the test tubes, the test tuberack should be extended at certain portions. The same feature areas areconfigured on the extended portion of the test tube rack for shiftdetection of the test tube rack. To implement the above configuration,the length of the test tube rack would be extended, which does not meetthe requirements in reality. Therefore, the configuration with twodetectors is selected in the present embodiment.

FIG. 9 shows a partial detail circuit diagram of a shift detectiondevice of the test tube rack for one embodiment of the presentapplication. An amplifier circuit 803 and a digital filter 804 areconfigured between a sensor 801 and a processing circuit 802 foramplifying the detection signals outputted from the sensor 801 andconducting a digital filtering for the amplified signals. The processingcircuit 802 acquires the initial voltage, the stop voltage and the limitvoltage from the digitally filtered signals. A driving circuit 805 isconfigured between the sensor 801 and the processing circuit 802 fordriving the sensor 801 to emit detection signals. In the presentembodiment, the processing circuit 802 is also capable of raising awarning (not shown) when the shifting process of the test tube rack isdetected as false.

In one embodiment of the analyzer pipeline system, the test tube rackthereof, the shift detection method and the device using the same,firstly, the test tube rack only includes the first feature areas andthe second feature areas for shift detection; the detecting area for thesensor avoids detecting the area of the test tubes so that the detectionsignals are not influenced by the reflective signals generated from thetest tubes and tags. Therefore, no test tube would be lost for detectionwhen the shifting process of the test tube is false so as to raise thereliability of this pipeline system. Secondly, a relative value signaldetecting algorithm in a feature area is implemented as the shiftdetection method disclosed in the present embodiment. The relative valuesignal detecting algorithm determines the shift of the test tube rackthrough detecting the relative multiple numbers between the peak partand the weak part of the detection signals. Therefore, sensitivityrequirements for the implemented reflective optical sensor could besignificant reduced. Sensitivity requirements could be satisfied by ageneral type reflective optical sensor so as to reduce the cost ofreflective optical sensors. Finally, when the test tube rack is notshifted to the right locating position at the first time shiftingprocess, it is possible to automatically re-shift the test tube rackthrough the above breakdown point recovering algorithm until the testtube rack is shifted to the right locating position. Since the timeinterval for previous shifting to the re-shifting process is quiteshort, the user would not notice the analyzer had ever broken down. Theabove embodiment is significantly more intelligent, so that the userexperience is accordingly better.

It is understandable for those skilled in the art that all or some ofthe processes disclosed in the embodiments of the present applicationare able to be implemented by instructing related hardware throughcomputer programs. The above programs are able to be stored in thereadable storage media of a computer. The above programs are able toinclude the implementation of all flow charts for all methods disclosedin the above embodiments in execution. The readable storage mediainclude but are not limited to: hard disc, optical disc, read-onlymemory (ROM) and random access memory (RAM).

Although the present disclosure has been described through specificembodiments, the present disclosure is not limited to the specificembodiments described above. Those of skill in the art should understandthat various modifications, alternatives and variations may be madebased on the present disclosure, which all should be within the scope ofprotection of the present disclosure. Furthermore, “an embodiment” or“another embodiment” mentioned above may represent differentembodiments, or may also be combined completely or partly in oneembodiment.

1. A test tube rack of an analyzer pipeline, wherein the test tube rackcomprises a plurality of test tube holders for holding test tubes,comprising: a light blocker configured at a side wall of the test tuberack and across multiple test tube holders, wherein a second featurearea is configured on the light blocker between two adjacent test tubeholders, a first feature area is configured between two adjacent secondfeature areas, and a step gap with a predetermined depth is configuredbetween the first feature area and a second feature area.
 2. The testtube rack of claim 1, wherein the second feature area is a groove thatis lower than the first feature area by the predetermined depth, or thesecond feature area is a protrusion that is higher than the firstfeature area by the predetermined depth.
 3. The test tube rack of claim1, wherein the predetermined depth is between 5 and 7 mm.
 4. The testtube rack of claim 1, wherein the light blocker is configured at anupper portion of the side wall of the test tube rack.
 5. A shiftdetection method implemented by using the test tube rack of claim 1,comprising: acquiring a detection signal outputted from a sensor duringa single shifting process of the test tube rack, and acquiring a stopvoltage from the detection signal when the single shifting process stopsand a limit voltage during the single shifting process; and determiningwhether a ratio of the limit voltage and the stop voltage satisfies afirst condition; if the first condition is satisfied, the singleshifting process of the test tube rack is determined as correct;otherwise, the single shifting process of the test tube rack isdetermined as false.
 6. The shift detection method of claim 5, furthercomprising: after acquiring the detection signal outputted from thesensor during the single shifting process of the test tube rack,acquiring an initial voltage from the detection signal during the singleshifting process of the test tube rack; and when determining whether theratio of the limit voltage and the stop voltage satisfies the firstcondition, also determining whether a ratio of the limit voltage and theinitial voltage satisfies a second condition; if the first and secondconditions are satisfied, the single shifting process of the test tuberack is determined as correct; otherwise, the single shifting process ofthe test tube rack is determined as false.
 7. The shift detection methodof claim 6, wherein: the first condition is the ratio of the limitvoltage and the stop voltage is larger than a first factor and thesecond condition is the ratio of the limit voltage and the initialvoltage is larger than a second factor; or the first condition is theratio of the limit voltage and the stop voltage is smaller than a firstfactor and the second condition is the ratio of the limit voltage andthe initial voltage is smaller than a second factor.
 8. The shiftdetection method of claim 5, further comprising: outputting a warningsignal by a warning device when the single shifting process of the testtube rack is determined as false; or after the single shifting processof the test tube rack is determined as false, controlling the test tuberack to conduct a re-shifting process, acquiring a detection signaloutputted from the sensor during the re-shifting process, andre-acquiring a stop voltage and a limit voltage during the re-shiftingprocess by considering the detection signal acquired during the previousshifting process; and determining whether a ratio of the re-acquiredlimit voltage and the re-acquired stop voltage satisfies the firstcondition; if the first condition is satisfied, the re-shifting processof the test tube rack is determined as correct; otherwise, controllingthe test tube rack to repeat the re-shifting process until there-shifting process of the test tube rack is determined as correct. 9.The shift detection method of claim 6, further comprising: outputting awarning signal by a warning device when the single shifting process ofthe test tube rack is determined as false; or after the single shiftingprocess of the test tube rack is determined as false, controlling thetest tube rack to conduct a re-shifting process, acquiring a detectionsignal outputted from the sensor during the re-shifting process, andre-acquiring an initial voltage, a stop voltage and a limit voltage forthe re-shifting process by considering the detection signal acquiredduring the previous shifting process; and determining whether a ratio ofthe re-acquired limit voltage and the re-acquired stop voltage satisfiesthe first condition, and whether a ratio of the re-acquired limitvoltage and the re-acquired initial voltage satisfies the secondcondition; if both conditions are satisfied, the re-shifting process ofthe test tube rack is determined as correct; otherwise, controlling thetest tube rack to repeat the re-shifting process until the re-shiftingprocess of the test tube rack is determined as correct.
 10. The shiftdetection method of claim 9, wherein the step of re-acquiring an initialvoltage, a stop voltage and a limit voltage for the re-shifting processcomprises: acquiring the initial voltage, the stop voltage and the limitvoltage from the detection signal outputted from the sensor and acquiredduring the re-shifting process; comparing the initial voltage, the stopvoltage and the limit voltage acquired during the re-shifting processwith the initial voltage, the stop voltage and the limit voltageacquired from the detection signal outputted from the sensor andacquired and buffered during the previous shifting process; selectingthe smaller one from the two initial voltages as a present initialvoltage; selecting the larger one from the two limit voltages as apresent limit voltage when the two limit voltages are maximum voltages,or selecting the smaller one from the two limit voltages as a presentlimit voltage when the two limit voltages are minimum voltages;selecting the re-acquired stop voltage acquired during the presentre-shifting process as a present stop voltage, or integrating insequence the detection signals outputted from the sensor and acquiredduring multiple shifting processes to generate an integrated detectionsignal; and acquiring the initial voltage, the stop voltage and thelimit voltage for the re-shifting process from the integrated detectionsignal.
 11. A detecting device using the test tube rack of claim 1 forshift detection, comprising: a voltage acquisition module for acquiringa detection signal outputted from a sensor during a single shiftingprocess of the test tube rack and a stop voltage from the detectionsignal when the single shifting process stops and a limit voltage fromthe detection signal during the single shifting process; and a shiftdetermination module for determining whether a ratio of the limitvoltage and the stop voltage satisfies a first condition; if the firstcondition is satisfied, the single shifting process of the test tuberack is determined as correct; otherwise, the single shifting process ofthe test tube rack is determined as false.
 12. The detecting device ofclaim 11, wherein the voltage acquisition module further acquires aninitial voltage from the detection signal at the beginning of the singleshifting process of the test tube rack after the detection signaloutputted from the sensor during the single shifting process of the testtube rack is acquired; and the shift determination module furtherdetermining whether a ratio of the limit voltage and the stop voltagesatisfies a first condition and also determining whether a ratio of thelimit voltage and the initial voltage satisfies a second condition; ifthe first and second conditions are satisfied, the single shiftingprocess of the test tube rack is determined as correct; otherwise, thesingle shifting process of the test tube rack is determined as false.13. The detecting device of claim 12, wherein: the first condition isthe ratio of the limit voltage and the stop voltage is larger than afirst factor and the second condition is the ratio of the limit voltageand the initial voltage is larger than a second factor; or the firstcondition is the ratio of the limit voltage and the stop voltage issmaller than a first factor and the second condition is the ratio of thelimit voltage and the initial voltage is smaller than a second factor.14. The detecting device of claim 11, wherein the shift determinationmodule outputs a warning signal when the shifting process of the testtube rack is determined as false, or further comprising: a re-shiftingmodule for controlling the test tube rack to conduct a re-shiftingprocess after the shifting process of the test tube rack is determinedas false, acquiring a detection signal outputted from the sensor duringthe re-shifting process and re-acquiring an initial voltage, a stopvoltage and a limit voltage for the re-shifting process by consideringthe detection signal acquired in the previous shifting process with thedetection signal acquired during the re-shifting process; wherein theshift determination module determines whether the ratio of there-acquired limit voltage and the re-acquired stop voltage satisfies thefirst condition; if the first condition is satisfied, the re-shiftingprocess of the test tube rack is determined as correct; otherwise, theshift determination module controls the test tube rack to repeat there-shifting process until the re-shifting process of the test tube rackis determined as correct.
 15. The detecting device of claim 12, whereinthe shift determination module outputs a warning signal when theshifting process of the test tube rack is determined as false, orfurther comprising: a re-shifting module for controlling the test tuberack to conduct a re-shifting process after the shifting process of thetest tube rack is determined as false, acquiring a detection signaloutputted from the sensor during the re-shifting process andre-acquiring an initial voltage, a stop voltage and a limit voltage forthe re-shifting process by considering the detection signal acquired inthe previous shifting process with the detection signal acquired duringthe re-shifting process; wherein the shift determination moduledetermines whether the ratio of the re-acquired limit voltage and there-acquired stop voltage satisfies the first condition and whether theratio of the re-acquired limit voltage and the re-acquired initialvoltage satisfies the second condition; if the first and the secondconditions are satisfied, the re-shifting process of the test tube rackis determined as correct; otherwise, the shift determination modulecontrols the test tube rack to repeat the re-shifting process until there-shifting process of the test tube rack is determined as correct. 16.The detecting device of claim 14, wherein the step of re-acquiring aninitial voltage, a stop voltage and a limit voltage for the re-shiftingprocess conducted by the re-shifting module further comprises: acquiringthe initial voltage, the stop voltage and the limit voltage from thedetection signal outputted from the sensor; considering the initialvoltage, the stop voltage and the limit voltage for the re-shiftingprocess with the initial voltage, the stop voltage and the limit voltageacquired from the detection signal buffer in the previous shiftingprocess; selecting the smaller one from the above two initial voltagesas a present initial voltage; selecting the larger one from the abovetwo limit voltages as a present limit voltage when the two limitvoltages are maximum voltages, or selecting the smaller one from abovetwo limit voltages as a present limit voltage when the two limitvoltages are minimum voltages; selecting the re-acquired stop voltageacquired in the present re-shifting process as a present end voltage; orintegrating detection signals outputted from the sensor in severalshifting processes in sequence to generate an integrated detectionsignal by the re-shifting module; and acquiring the initial voltage, thestop voltage and the limit voltage from the integrated detection signalby the re-shifting module.
 17. An analyzer pipeline system, comprising:an analyzer; a test tube rack of claim 1; a driving apparatus fordriving the test tube rack; a sensor for detecting a first feature areaand a second feature area during a shifting process of the test tuberack and outputting a corresponding detection signal; and a processorcomprising a detection device for detecting the shift of the test tuberack, wherein the detection device is coupled to an output of the sensorand receives the detection signal outputted from the sensor to determinewhether the shifting process of the test tube rack is correct.
 18. Theanalyzer pipeline system of claim 17, wherein: the detecting deviceacquires an initial voltage at the beginning of the shifting process, astop voltage at the end of the shifting process and a limit voltagebetween the beginning and the end of the shifting process based on thedetection signal outputted from the sensor corresponding to the firstfeature area and the second feature area; and the detecting device alsodetermines whether a ratio of the limit voltage and the stop voltagesatisfies the first condition and also whether the ratio of the limitvoltage and the initial voltage satisfies the second condition; if bothof the above conditions are satisfied, the shifting process of the testtube rack is determined as correct; otherwise, the shifting process ofthe test tube rack is determined as false.
 19. The analyzer pipelinesystem of claim 18, wherein: the detecting device controls the test tuberack to conduct a re-shifting process after the shifting process of thetest tube rack is determined as false, acquires a detection signaloutputted from the sensor during the re-shifting process and re-acquiresan initial voltage, a stop voltage and a limit voltage for there-shifting process by considering the detection signal acquired in aprevious shifting process with the detection signal acquired during there-shifting process; and the detecting device also determines whetherthe ratio of the re-acquired limit voltage and the re-acquired stopvoltage satisfies the first condition and whether the ratio of the limitvoltage and the initial voltage satisfies the second condition; if thefirst and the second conditions are satisfied, the re-shifting processof the test tube rack is determined as correct; otherwise, the shiftdetermination module controls the test tube rack to repeat there-shifting process until the re-shifting process of the test tube rackis determined as correct.
 20. The analyzer pipeline system of claim 17,wherein the sensor comprises a first sensor configured at a test tubedetecting position and a second detector configured at a samplecollecting position.